Measuring the mind: assessing cognitive change in clinical drug trials
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چکیده
منابع مشابه
Validation of Instruments for Assessing Drug Safety Management During the Conduction of Clinical Trials
Background The management of drug safety with the collection of reliable safety data during the conduction of clinical trials conduct is essential for the registry and marketing of products. The systematic evaluation of this process, based on objective measures, requires the application of quality instruments. This study was aimed to design and validate eight instruments through the components ...
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Overall survival remains the gold standard for the demonstration of clinical benefit. An improvement in overall survival is a direct clinical benefit to patients. An analysis of overall survival requires larger patient numbers and longer follow-up than other endpoints. Survival analysis may be confounded by subsequent therapies. Time to progression usually requires smaller clinical trials and m...
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while preclinical research answers basic questions about a drug’s safety, it is not a substitute for studies of ways the drug will interact with the human body. “clinical research” refers to studies, or trials, that are done in people 1,2. as the developers design the clinical study, they will consider what they want to accomplish for each of the different clinical research phases and begin the...
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The interaction between the patient’s expected outcome of an intervention and the inherent effects of that intervention can have extraordinary effects. Thus in clinical trials an effort is made to conceal the nature of the administered intervention from the participants in the trial i.e. to blind it. Yet, in practice perfect blinding is impossible to ensure or even verify. The current standard ...
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Addiction to drugs, such as heroin, cocaine and alcohol, exacts great human and financial costs on society. Various evidence-based pharmacological and psychosocial interventions are currently used in the treatment of drug addiction but they do not produce adequate therapeutic benefits in every patient. Further, barriers such as financial cost, lack of availability, or perceptions of existing tr...
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ژورنال
عنوان ژورنال: Expert Review of Clinical Pharmacology
سال: 2008
ISSN: 1751-2433,1751-2441
DOI: 10.1586/17512433.1.4.471